Vitamin B12, don't overdo it! Incorrect dosage can be toxic. The signs to watch out for

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Elia Tabuenca García
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Vitamin B12 is essential for the body to function properly, but excessive supplementation can have side effects.

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Vitamin B12 is essential for the body to function properly, but excessive supplementation can have side effects.





La Vitamin B12 it is an essential nutrient for the proper functioning of the body. THE symptoms of a deficiency of vitamin B12 include:

  • fatigue, 
  • bad mood,
  • nerve problems. 

For this reason, many people take B12 supplements; however, it is possible to take too much to show signs of intoxication.

Vitamin B12: what it is, dosage and symptoms of intoxication

Vitamin B12 plays a essential role in the formation of red blood cells, in cellular metabolism, in nerve function and in the production of DNA, the molecules within cells that carry genetic information. When taken in appropriate doses, vitamin B12 supplements are generally considered safe, but an overdose could cause an unusual sensation in our body.

La Recommended daily amount of vitamin B12 for adults is 2,4 micrograms. The body only absorbs the amount it needs and any excess is excreted through the urine.

High doses of vitamin B12 cause potential toxicity; the symptoms of intoxication I'm:

  • Headache
  • Nausea and vomit
  • Diarrhea
  • Fatigue or weakness
  • Tingling sensation in the hands and feet

Additionally, a B12 overdose has been shown that it can cause acne and rosacea, a skin condition that causes redness and pus-filled bumps especially on the face, but also diabetes and kidney disease. (Read also: Vitamin B12 supplements)

Some studies have observed that participants who received high-dose B vitamins had a increased risk of heart attack, ictus and death, compared to those who received a placebo.



Risk of toxicity in pregnancy

Uno study looked at how taking vitamins could lead to autism risk for offspring in pregnant women. The study included 1257 mother-child pairs, recruited at birth and followed prospectively in infancy.

THEmaternal multivitamin supplementation was assessed through an interview with a questionnaire; Maternal plasma folate and vitamin B12 were measured from samples taken two or three days after birth.

The study found that self-reported moderate (three to four times per week) supplementation during pregnancy was associated with a reduced risk of autism, and high (over five times per week) supplementation was associated with increased risk of autism. Very high levels of maternal plasma folate at birth have increased risk of autism two and a half times. (Read also: VITAMIN B12: WHAT ARE THE SAFE SOURCES?)

Obviously, this study does not question the importance of adequately consuming folic acid and vitamin B12 during pregnancy; rather, it raises new questions about the impact of extremely high plasma folate levels and vitamin B12 exposure in utero on early brain development.



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