Breast Cancer: This substance in cardamom could be the key to blocking aggressive cancers

Breast Cancer: This substance in cardamom could be the key to blocking aggressive cancers

According to a new study, cardamom contains a substance known as cardamonin, capable of blocking the development of some of the most aggressive breast cancers. A fundamental discovery in research to pave the way for new and effective treatments.



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According to recent research, cardamom may be the key to dealing with aggressive types of breast cancer.



According to scholars this effect is to be attributed to a natural compound called cardamonina which is found in the spice, and is capable of killing cancer cells.

About 10-15% of breast cancers are known as 'triple-negative', as they are more aggressive and deadly. But now scientists have made a promising discovery that could pave the way for new treatments.

The author of the study, Dr. Patricia Mendonca said:

There is a fundamental need to study medicinal plants as a new way to fight this cancer.

(Read also: Cardamom: how to grow it at home from seeds in the pantry)

A systematic review

His team studied how the cardamonina it affected the expression of a gene dubbed PD-L1 found in cancer cells.

The gene plays a vital role in helping breast cancer cells escape the immune system.

They tested the spice on cancer cells derived from women of African American descent, and women of European descent.

Cardamonin was found to kill cancer cells of both groups, but only limits PD-L1 expression in European women. Genetic variations between races could explain why the cancer cells responded differently to the spice.

Cardamom is a spice obtained from the seeds of various plants of the genera Elettaria and Amomum. Both are native to the Indian subcontinent, Indonesia, and tropical and subtropical Asia.

Today, the precious spice is also grown in Guatemala, Malaysia and Tanzania and is the third most expensive spice, after saffron and vanilla.

A common ingredient in Indian cooking and Nordic baking, cardamom has a strong and unique taste, with an intensely aromatic scent.



The first references to cardamom as a medicinal spice are found in the Ayurvedic literatures of India, but also the ancient Greek doctors, Dioscorides and Hippocrates, wrote about its therapeutic properties, identifying it as a digestive aid.

Seeds, oils and extracts have been used in traditional medicine for centuries; a 2009 study showed that it significantly reduced the blood pressure.

(Read also: Breast cancer: biomarkers for early diagnosis identified for the first time thanks to breast milk )

Other studies have shown that cardamom powder can increase the activity of certain enzymes, which help fight cancer. However, another research showed that a certain compound in the spice prevented oral cancer cells from multiplying.

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Photos: Experimental Biology


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