Peanuts: Unexpected and serious side effect of overconsumption discovered on cancer patients

    Peanuts: Unexpected and serious side effect of overconsumption discovered on cancer patients

    Eating too many peanuts could speed up the spread of cancer in patients already suffering from the disease

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    According to a study conducted by the University of Liverpool, eating too much peanuts could speed up the spread of cancer in patients already suffering from this disease. This is due to a protein contained in dried fruit.





    When the cancer it begins to spread to areas of the human body other than those where it was born (through metastases), the disease becomes difficult to treat and the patient often dies. The disease tends to spread throughout the body, but there are factors that can influence the spread of the tumor, favoring a faster and more acute development - and food is certainly the most important of these: there are in fact foods that more than others they favor the development of metastases and, therefore, the deterioration of health.

    One of these foods is undoubtedly peanuts. According to the researchers of theUniversity of LiverpoolPeanuts contain a protein that binds to carbohydrates (called peanut agglutinin or PNA) that enters the bloodstream, interacts with endothelial cells (the cells that line the inside of the walls of the heart, blood vessels, and lymphatics) and pushes them to produce cytokines - protein molecules responsible for spreading metastases within the human body.

    Already in a previous study, researchers had shown that PNA in human blood binds to a special sugar chain that occurs mainly in cancerous and pre-cancerous cells and that interacts with a larger protein found on the surface of cancer cells. into the bloodstream. This interaction causes changes in the larger protein: the surface of the cancer cells becomes more 'sticky' and thus manages to attach itself to the blood vessels; in addition, cancer cells are able to form small 'clusters' that allow them to live longer in the bloodstream, spreading more throughout the body.

    While more research is needed in this area, these studies show how frequent and excessive consumption of peanuts in cancer patients can increase the risk of spread of metastases. The possible impacts of peanut consumption on patient survival and disease progression require further epidemiological investigations, but in any case, researchers advise against the intake (frequent or moderate) of American peanuts for cancer patients, because the effects of this fruit on their health are not yet well defined. 



    It should be emphasized, however, that a very high dose of peanuts (greater than 250g consumed at one time) is required to observe negative effects on the spread of metastatic cells - while a moderate dose of peanuts contains a minimal concentration of PNA which it would have no health consequences. 

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    Fonte: Carcinogenesis

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