Drink grapefruit juice to reduce your intake of anticancer drugs. According to a study by the University of Chicago Medicine, coordinated by Dr. Ezra Cohen and published in the August edition of the journal Clinical Cancer Research, drinking the juicy liquid derived from this citrus fruit every day increases the effects of sirolimus, an effective drug for more than three times. the fight against cancer.
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Drink grapefruit juice to reduce your intake of anticancer drugs. According to a study by the University of Chicago Medicine, coordinated by Dr. Ezra Cohen and published in the August edition of the journal Clinical Cancer Research, drinking the juicy liquid derived from this citrus every day increases more than three times the effects of the sirolimus, effective drug for fight against cancer.
After dividing cancer patients into three groups, the researchers gave them sirolimus alone, in combination with the ketoconazole, a drug that increases sirolimus levels 5 times, and along with grapefruit juice, found that those who drank grapefruit needed drug levels of 25-35 mg per week. A significantly reduced amount compared to those who had only taken the drug, for a dose equal to 90 mg per week.
“Grapefruit juice and drugs that work by a similar mechanism greatly increase the levels of these drugs in the blood. Controlled administration of the juice could increase the efficacy and availability of drugs such as sirolimus“Explains Ezra Cohen. How? It would inhibit those enzymes, present in the intestine, that break down sirolimus, as well as other drugs.
Compared to ketoconazole, however, grapefruit juice it is neither dangerous nor toxic. And it does not even present problems related to the maximum dosage. This, the authors explain, provides “an agent who can significantly increase bioavailability and reduce the costs of prescription drugs ”. In reality, none of the patients involved in the study managed to defeat the cancer, but in 30% of cases the researchers were also able to stabilize the tumor in the medium to long term.