Vitamin D deficiency has been associated with acute coronary syndrome. New and recent research sheds light on this connection
Don't store avocado like this: it's dangerousVitamin D deficiency has been associated with acute coronary syndrome. New and recent research sheds light on this connection
The shortage of vitamin D it is a problem that affects at least one billion patients worldwide. The calcitriolo 1,25 (OH) 2D3 has several systemic effects, including anti-inflammatory properties, antithrombotic e antiaterosclerotiche which explain its cardioprotective effects.
The precise association between vitamin D, its metabolites, and the value of supplements in acute coronary syndrome (ACS) is still controversial. But a new and recent study aims to investigate the association between vitamin D2, D3 and metabolites and acute coronary syndrome in patients undergoing coronary angiography. (Read also: How long to spend in the sun to recharge with Vitamin D [VIDEO])
A systematic review
This study analyzed 73 adult patients with acute coronary syndrome undergoing coronary angiography and compared with 50 patients without coronary artery disease, matched by age and sex in the period from June 2019 to July 2019. Echocardiography and coronary angiography were performed for all cases, and plasma vitamin D and its metabolites were measured at admission for all participants.
The results
La vitamin D and its metabolites they were statistically and significantly lower in patients with acute coronary syndrome. The analysis revealed, therefore, that low levels of vitamin D could cause the onset of acute coronary syndrome; the other significant predictors werehigh systolic blood pressure (BP), the high total cholesterol and low-density lipoprotein cholesterol. Interestingly, vitamins D2 and D3 did not significantly predict the onset of coronary syndrome (p> 0,05). Consequently, no statistically significant association was found between the number of affected coronary vessels and the vitamin D metabolites. Furthermore, there was no statistically significant correlation between vitamin D and its metabolites, and the measured left ventricular ejection fraction. by echocardiography.
There was, however, a strong association between vitamin D and all of its metabolites with coronary syndrome. Hence, low levels of calcitriolo they can cause this disease, but not a deficiency of vitamins D2 and D3. In fact, according to the researchers, large randomized controlled trials are needed to verify the benefits of vitamin D supplementation in patients with acute coronary syndrome.
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