The secret against obesity is in our genes, new discovery opens the doors of personalized therapies

Who I am
Carlos Laforet Coll
@carloslaforetcoll
Author and references

According to research, obesity is linked to genetics. This study could help develop new therapeutic strategies

Don't store avocado like this: it's dangerous

According to research, obesity is linked to genetics. This study could help develop new therapeutic strategies





A new study helped shed light on genetic pathways underlying obesity. The findings could help develop more personalized ways to help overweight people maintain a healthy weight. (Read also: Massive DNA study finds rare genetic variants that protect against obesity)

THEWorld Health Organization estimates that over four million people die each year from being overweight or obese. In fact, this is one of the most common conditions, on which however there is still so much to understand, especially as regards the biological mechanisms connected to it. 

The work was supported by the Guy and St Thomas Biomedical Research Center of the National Institute for Health Research (NIHR), and is the largest study of its kind, which examined the genomics and metabolite levels, which are the molecules produced when the body breaks down food.

Specifically, 722 levels of circulating metabolites were analyzed in 8809 subjects of European origin. These analyzes identified as many as 74 previously unknown genomic regions, which influence how people's bodies break down food into energy. Some of the metabolites examined are related to the BMI, Body Mass Index, and could give an idea of ​​how obesity develops in some individuals.

This is a very early research, but in the future these findings could help develop different approaches for help obese patients to achieve and, above all, maintain a healthy and normal weight.

This study is the largest-scale research conducted to date, and its results improve knowledge on the genetic mechanisms that control human metabolism, and the results have great potential for identifying new targets and developing new therapeutic strategies.


Follow us on Telegram | Instagram | Facebook | TikTok | Youtube


Photos: MDPI

Sull 'obesity could it be interesting for you:

  • Obesity: for scientists it does not depend on how much, but above all on WHAT we eat
  • Block hunger by acting on the brain: can this drug really fight obesity?
  • Mexican scientists create low GI barley tortilla against diabetes and obesity
  • Obesity changes the brain to reduce gray matter. Science confirms this
  • The snack tax is more effective against obesity than the soft drink tax, the study in the UK
add a comment of The secret against obesity is in our genes, new discovery opens the doors of personalized therapies
Comment sent successfully! We will review it in the next few hours.