Genes, hormones and the environment can generate autistic behaviors: if autism has a specific cause, perhaps it can be found in this triad of factors. A study by the Irccs Santa Lucia Foundation and the Bio-Medico Campus says so
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Geni, hormones e environment can generate autistic behaviors: if autism has a specific cause, perhaps it can be found in this one triad of factors. says one study dell 'Irccs Santa Lucia Foundation and the Bio-Medico Campus, conducted in collaboration with the Istituto Superiore di Sanità and the University of Pisa and published online on Neurotoxicology.
A research that confirms the "multifactorial pathogenetic hypothesis and therefore tries to propose a model that takes these components into account to detect autism risk. A disease, autism, which begins before the age of three and is recognized by the first unmistakable symptoms: the child has difficulties with language, communication and relationships with others. And he isolates himself. Throwing himself, and his parents with him, into solitude.
Why it develops still remains a mystery and, once cleared trivalent vaccine as a possible cause, the belief among experts remains that surely the genetic factor is of considerable importance. In addition, statistical studies, experiments and clinical realities have also given a large share of responsibility to hormonal variations during development and to possible environmental toxicants.
Starting from these elements, genes, hormones and the environment, which interact at a cellular and behavioral level, three years ago, thanks to a grant from the US Autism Speaks foundation, the research of the Irccs Santa Lucia Foundation and Campus Bio was launched. -Medico, in collaboration with the Istituto Superiore di Sanità and the University of Pisa.
THE EXPERIMENTS - The studies were performed by analyzing the effects of sex hormones, the genetic alteration of the synthesis of relin (a fundamental protein in embryogenesis, the development of the embryo from the fertilized egg) and exposure to mercury in the period prenatal and perinatal on the development of autistic behaviors. The result is that the interaction between these elements, therefore the coexistence of hormonal, genetic and environmental conditions, induced the appearance of different indicators of autistic disorder both at the cellular and behavioral level.
A step forward towards the knowledge of this serious disease? Likely. The fact remains that, for now, autistic children - but also adults - need, albeit in their very private world, to know that they can express freely as they can.
Germana Carillo
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