BPA passed from a pregnant woman to her baby via the placenta can negatively impact the brain development of the fetusDon't store avocado like this: it's dangerous
BPA passed from a pregnant woman to her baby via the placenta can negatively impact the brain development of the fetus
In a new one study Scientists at the University of Missouri have shown that direct transmission of bisphenol A (BPA) from a mother to her developing baby through the placenta could have a negative impact on the brain development of the fetus. According to the researchers, more attention should be paid to how this temporary organ affects the brain development of the future baby.
The placenta is only a temporary organ, which helps the exchange of nutrients and wastes between mother and baby during pregnancy, but the way it responds to toxic substances such as BPA during pregnancy can lead to long-term health consequences. .
A systematic review
The team focused on the role of microRNAs within the placenta, which are known to be key mediators in the regulation of cellular functions, including neural development and the identification of certain markers for cancer. These microRNAs play a role in how the effects of BPA exposure can lead to neurological disorders later in life. They can be packaged inside extracellular vesicles, and can be transported to distant organs within the body.
It is assumed that by changing the pattern of microRNAs in the placenta, these small molecules can reach the brain, causing damaging effects. Even before brain neurons are developed, these microRNA packets may already be driving fetal brain development; such changes may also be different in female than male fetuses.
Il BPA is used in many household items such as plastic water bottles, food containers and in the epoxy coating of metal food cans. Exposure can occur during the simple act of microwaving food inside polycarbonate plastic food containers.
While several efforts have been made to make products “BPA-free,” the more than decade-long debate over what are considered safe levels of BPA exposure continues; numerous studies have examined the possible health consequences, including neurobehavioral disorders, diabetes, obesity and various reproductive deficiencies.
By identifying the relationship between these microRNAs and fetal brain development through exposure to BPA, targeted therapies could be developed to help prevent or reverse some of the damaging effects of exposure. Future studies should include examining the relationship between the placenta and the brain outside the body, through the use of cell culture systems.
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Photos: Future Medicine
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