Autism: does it already develop during pregnancy?

    Autism: does it already develop during pregnancy?

    According to an American research, autism already develops during pregnancy when the cerebral cortex develops

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    After the controversy of recent days regarding the alleged appearance of autism following the administration of the trivalent vaccine, news now arrives from San Diego of a discovery that helps to better clarify the phenomenon of autism and in particular answers the question: when and why it develops? According to the research, the onset of autism would already occur during pregnancy and it would be due to an incorrect growth of brain cells.





    To reach this conclusion, the University of California study published in the New England Journal of Medicine analyzed 25 genes of the brain tissue of a group of children deceased, some with autism, some without. By carefully evaluating and comparing the brain state of the sampled babies, the scientists were able to come up with what they consider proof that autism develops when the baby is still a fetus in the mother's womb.

    To provoke the appearance of the disease would be a wrong process in the construction of the cerebral cortex at the time of the child's formation as explained by one of the authors of the study Eric Courchesne: “The construction of the brain of a child during pregnancy is a process that includes the creation of a cortex with six layers. We discovered the presence of disrupted developmental areas in these cortical layers in most children with autism and we created the first three-dimensional model of the areas of the brain where these layers of the cortex failed to develop normal cellular stratifications ".

    The defect, which has been highlighted in children with autism, is therefore observed at the level of the cerebral cortex (in particular in the temporal and frontal cortex) in which, in the first 3 months of pregnancy, cell lumps would form. This would indicate that "the fundamental phase of early development to create six different layers with particular types of brain cells - which begins in prenatal life - has been interrupted in the womb".

    The cortex is essential for the regulation of several functions (communicative, emotional, cognitive) all particularly problematic spheres in subjects with autism. Why abnormal cells form in these children is still unclear, the researchers say it may be genetic mutations or da environmental factors.



    Experts have called this "preliminary" research underlining the fact that new studies will be needed to understand if this phenomenon is the cause of all cases of autism.



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