Alzheimer's: dementia can be diagnosed with a blood test, the revolutionary discovery

Who I am
Elia Tabuenca García
@eliatabuencagarcia
Author and references

A blood test using atomic force microscopy technology appears to be effective as a diagnostic test for Alzheimer's

Don't store avocado like this: it's dangerous

A blood test using atomic force microscopy technology appears to be effective as a diagnostic test for Alzheimer's





Detect the Alzheimer's disease in those affected it is quite invasive, as long and complex examinations and procedures must be performed until the diagnosis is clear and precise.

A research team, on the other hand, is developing a blood test that will allow for a reliable diagnosis, using atomic force microscopy (AFM). The researchers recently published the first results of the study in the journal Science Advances.

A systematic review

The study conducted by physicist Peter Nirmalraj aimed to understand the molecular pathogenesis of Alzheimer's, to enable new diagnostic and therapeutic approaches.

The new research took it one step further as it deciphered the exact role of the beta-amyloid peptides and protein tau associated with neurodegenerative disease. Nirmalraj therefore set out not only to detect the mere presence of the suspect proteins, but also to determine their variable shape, as well as their quantity.

Current methods allow for the determination of the total amount of both proteins in body fluids. However, these techniques do not allow for visualization of differences in the shape and condition of the protein accumulations. The researcher is working on new technologies capable of enabling nanoscale observations in blood.

The pilot study looked at blood samples from 50 patients and 16 healthy subjects, using AFM technology the surfaces of about 1000 red blood cells per person were analyzed without knowing anything about their state of health.

The size, structure and consistency of the protein accumulations present on the blood cells were measured. After thousands of red blood cells, the team eagerly awaited the comparison of the results with clinical data from neurologists and, in fact, the researchers were able to discern a pattern that matched the stage of the disease: People with the disease had large amounts of protein fibers consisting of beta-amyloid peptides and tau proteins.



Thus, if a reliable blood test based on this method could be developed, people suspected of Alzheimer's would be spared the unpleasant puncture of the spinal canal, currently the only way to accurately diagnose the disease.

Follow us on Telegram | Instagram | Facebook | TikTok | Youtube

Source: Science.org

Could it be interesting for you:

  • Alzheimer's: Scientists discover for the first time what happens in the brain when it goes wild
  • Scientists discover a rare and aggressive form of Alzheimer's, which begins around age 40
  • Alzheimer's: If you suffer from herpes you may be more likely to suffer from these neurodegenerative diseases
  • Mozart effect: music is an effective "cure" for Alzheimer's patients, the study
  • Pollution and Alzheimer's: Improving air quality reduces risk, now three new studies confirm this
  • The most effective meditation of medicines on Alzheimer's patients. The Indian study
  • Omega-3 supplements: discovered this benefit in Alzheimer's patients
  • The untold story of the dancer with Alzheimer's that thrilled us
  • Oxytocin against Alzheimer's: does the love hormone block cognitive decline? The new study
add a comment of Alzheimer's: dementia can be diagnosed with a blood test, the revolutionary discovery
Comment sent successfully! We will review it in the next few hours.